Synthesis and antibacterial activity of N-amino-derivatives of condensed pyridines

Synthesis and antibacterial activity of N-amino-derivatives of condensed pyridines

A method based on condensed 4-cyanopyridinethiones using O -tosylhydroxylamine as the aminating agent was developed for preparing tosylates of N -amino-derivatives of pyrano[3,4- c ]pyridines; 5,6,7,8-tetrahydroisoquinolines; and cyclopenta[ c ]pyridines. The antibacterial activity of the synthesize...

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Veröffentlicht in:Pharmaceutical chemistry journal 2013-08, Vol.47 (5), p.257-260
Hauptverfasser: Paronikyan, E. G., Hakobyan, Sh. F., Noravyan, A. S., Hajos, G., Dashyan, Sh. Sh, Paronikyan, R. V., Stepanyan, G. M.
Format: Artikel
Sprache:eng
Schlagworte:
Antibacterial agents
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Pyridine
Resveratrol
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Zusammenfassung:A method based on condensed 4-cyanopyridinethiones using O -tosylhydroxylamine as the aminating agent was developed for preparing tosylates of N -amino-derivatives of pyrano[3,4- c ]pyridines; 5,6,7,8-tetrahydroisoquinolines; and cyclopenta[ c ]pyridines. The antibacterial activity of the synthesized compounds was assessed.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-013-0940-3