Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis — A randomized, placebo-controlled, pilot study

Curcumin, an active ingredient of turmeric with anti-inflammatory properties, has been demonstrated to be useful in experimental models of ulcerative colitis (UC). It's efficacy in humans needs to be investigated. A randomized, double-blind, single-centre pilot trial was conducted in patients w...

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Veröffentlicht in:	Journal of Crohn's and colitis 2014-03, Vol.8 (3), p.208-214
Hauptverfasser:	Singla, Vikas, Pratap Mouli, Venigalla, Garg, Sushil Kumar, Rai, Tarun, Choudhury, Bikash Narayan, Verma, Prashant, Deb, Rachana, Tiwari, Veena, Rohatgi, Sarika, Dhingra, Rajan, Kedia, Saurabh, Sharma, Piyush Kumar, Makharia, Govind, Ahuja, Vineet
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Rectal Adult Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Colitis, Ulcerative - drug therapy Colitis, Ulcerative - pathology Curcumin Curcumin - administration & dosage Curcumin - therapeutic use Drug Therapy, Combination Endoscopy, Gastrointestinal Enema Female Humans Male Mesalamine - therapeutic use Middle Aged NCB-02 Pilot Projects Remission Induction - methods Severity of Illness Index Ulcerative colitis Young Adult
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Beschreibung
Zusammenfassung:	Curcumin, an active ingredient of turmeric with anti-inflammatory properties, has been demonstrated to be useful in experimental models of ulcerative colitis (UC). It's efficacy in humans needs to be investigated. A randomized, double-blind, single-centre pilot trial was conducted in patients with distal UC (
ISSN:	1873-9946 1876-4479
DOI:	10.1016/j.crohns.2013.08.006