Restoration of Articular Cartilage

➤ Novel (i.e., quantitative and semiquantitative) cartilage imaging techniques can evaluate cartilage composition to augment information obtained from traditional magnetic resonance imaging sequences that detail morphology.➤ A well-defined role for drugs leading to chondroprotection has not yet been...

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Veröffentlicht in:Journal of bone and joint surgery. American volume 2014-02, Vol.96 (4), p.336-344
Hauptverfasser: Moran, Cathal J, Pascual-Garrido, Cecilia, Chubinskaya, Susan, Potter, Hollis G, Warren, Russell F, Cole, Brian J, Rodeo, Scott A
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Sprache:eng
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Zusammenfassung:➤ Novel (i.e., quantitative and semiquantitative) cartilage imaging techniques can evaluate cartilage composition to augment information obtained from traditional magnetic resonance imaging sequences that detail morphology.➤ A well-defined role for drugs leading to chondroprotection has not yet been determined.➤ Shortcomings of bone marrow stimulation include limited production of hyaline repair tissue, unpredictable repair cartilage volume, and a negative impact on later cellular transplantation if required.➤ The role of biological augments, such as cellular concentrates or platelet-rich plasma, remains undefined. When their use is reported in the literature, it is important that their process of production and characterization be detailed.➤ Rehabilitation programs, incorporating controlled exercise and progressive partial weight-bearing, are an important part of cartilage repair surgery and should be detailed in reports on operative techniques applied.➤ Malalignment, meniscal injury, and ligament deficiency should be corrected in a staged or concomitant fashion to reduce the overall likelihood of mechanical failure in cartilage repair surgery.
ISSN:0021-9355
1535-1386
DOI:10.2106/JBJS.L.01329