Factors predicting response to hepatitis B vaccination in patients with inflammatory bowel disease

Highlights • We assess which factors affect the response to hepatitis B vaccination in IBD. • Long-term progression of IBD decreases the response to hepatitis B vaccination. • Low levels of serum albumin decrease the response to hepatitis B vaccination. • Treatment with corticosteroids decreases the...

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Veröffentlicht in:	Vaccine 2013-06, Vol.31 (30), p.3065-3071
Hauptverfasser:	Sempere, Laura, Almenta, Isabel, Barrenengoa, Julio, Gutiérrez, Ana, Villanueva, Cesar O, de-Madaria, Enrique, García, Vicente, Sánchez-Payá, José
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Albumin Allergy and Immunology Applied microbiology Biological and medical sciences Cohort Studies Drug therapy Female Fundamental and applied biological sciences. Psychology Hepatitis hepatitis B Hepatitis B - prevention & control Hepatitis B Antibodies - blood Hepatitis B Antibodies - immunology hepatitis B antigens Hepatitis B Surface Antigens - blood Hepatitis B Surface Antigens - immunology Hepatitis B Vaccines - administration & dosage Hepatitis B Vaccines - immunology Hepatitis B virus Hepatitis B virus - immunology Human viral diseases Humans Immunization immunosuppression (therapy) Immunosuppression - adverse effects Infectious diseases Inflammatory bowel disease Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - therapy Male Medical sciences Microbiology Middle Aged Miscellaneous monitoring Multivariate analysis patients people prediction Preventive medicine serum albumin Vaccination vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Synthetic - administration & dosage Vaccines, Synthetic - immunology Viral diseases Viral hepatitis Virology
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Beschreibung
Zusammenfassung:	Highlights • We assess which factors affect the response to hepatitis B vaccination in IBD. • Long-term progression of IBD decreases the response to hepatitis B vaccination. • Low levels of serum albumin decrease the response to hepatitis B vaccination. • Treatment with corticosteroids decreases the response to hepatitis B vaccination.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2013.04.059