Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines

Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines

C–H, N–H dehydrogenative coupling of quinoline N-oxides with lactams/cyclamines has been achieved in the presence of the Cu(OAc)2 catalyst to give good to excellent yields. This study provides a new strategy for the construction of a 2-aminoquinoline skeleton via direct functionalization of aryl C–H...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2013-10, Vol.15 (20), p.5198-5201
Hauptverfasser: Li, Gang, Jia, Chunqi, Sun, Kai
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 5201
container_issue 20
container_start_page 5198
container_title Organic letters
container_volume 15
creator Li, Gang
Jia, Chunqi
Sun, Kai
description C–H, N–H dehydrogenative coupling of quinoline N-oxides with lactams/cyclamines has been achieved in the presence of the Cu(OAc)2 catalyst to give good to excellent yields. This study provides a new strategy for the construction of a 2-aminoquinoline skeleton via direct functionalization of aryl C–H bonds.
doi_str_mv 10.1021/ol402324v
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1499131422</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1499131422</sourcerecordid><originalsourceid>FETCH-LOGICAL-a315t-f76285ac474d51a818575d212a3abdcc4e388528206da0136b2c589e15aea09a3</originalsourceid><addsrcrecordid>eNptkMtOwzAQRS0EoqWw4AdQNkiwCPUjTpMlCq9KFRUSrKOpPaWpnLjYSaGs-AV-kS8h0NIVqzkanbnSXEKOGb1glLO-NRHlgkfLHdJlkotwQCXf3XJMO-TA-zmlrN2k-6TDI5oKKeMu8ZldLNCFGdRgVu-og2FVoyutQdUYcMEVzlba2WesoC6WGFyWhW7JVv2Wql8K7DR4aIrKmqLC4P7r43P8Vmj0wWtRz4IRqBpK389WykB7gv6Q7E3BeDzazB55url-zO7C0fh2mF2OQhBM1uF0EPNEgooGkZYMEpbIgdSccRAw0UpFKJJE8oTTWANlIp5wJZMUmQQEmoLokbN17sLZlwZ9nZeFV2gMVGgbn7MoTZlgEeeter5WlbPeO5zmC1eU4FY5o_lPx_m249Y92cQ2kxL11vwrtRVO1wIon89t46r2y3-CvgGHC4Ur</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1499131422</pqid></control><display><type>article</type><title>Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines</title><source>ACS Publications</source><creator>Li, Gang ; Jia, Chunqi ; Sun, Kai</creator><creatorcontrib>Li, Gang ; Jia, Chunqi ; Sun, Kai</creatorcontrib><description>C–H, N–H dehydrogenative coupling of quinoline N-oxides with lactams/cyclamines has been achieved in the presence of the Cu(OAc)2 catalyst to give good to excellent yields. This study provides a new strategy for the construction of a 2-aminoquinoline skeleton via direct functionalization of aryl C–H bonds.</description><identifier>ISSN: 1523-7060</identifier><identifier>EISSN: 1523-7052</identifier><identifier>DOI: 10.1021/ol402324v</identifier><identifier>PMID: 24093556</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><ispartof>Organic letters, 2013-10, Vol.15 (20), p.5198-5201</ispartof><rights>Copyright © 2013 American Chemical Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a315t-f76285ac474d51a818575d212a3abdcc4e388528206da0136b2c589e15aea09a3</citedby><cites>FETCH-LOGICAL-a315t-f76285ac474d51a818575d212a3abdcc4e388528206da0136b2c589e15aea09a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/ol402324v$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/ol402324v$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>314,776,780,2752,27053,27901,27902,56713,56763</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24093556$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Gang</creatorcontrib><creatorcontrib>Jia, Chunqi</creatorcontrib><creatorcontrib>Sun, Kai</creatorcontrib><title>Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines</title><title>Organic letters</title><addtitle>Org. Lett</addtitle><description>C–H, N–H dehydrogenative coupling of quinoline N-oxides with lactams/cyclamines has been achieved in the presence of the Cu(OAc)2 catalyst to give good to excellent yields. This study provides a new strategy for the construction of a 2-aminoquinoline skeleton via direct functionalization of aryl C–H bonds.</description><issn>1523-7060</issn><issn>1523-7052</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNptkMtOwzAQRS0EoqWw4AdQNkiwCPUjTpMlCq9KFRUSrKOpPaWpnLjYSaGs-AV-kS8h0NIVqzkanbnSXEKOGb1glLO-NRHlgkfLHdJlkotwQCXf3XJMO-TA-zmlrN2k-6TDI5oKKeMu8ZldLNCFGdRgVu-og2FVoyutQdUYcMEVzlba2WesoC6WGFyWhW7JVv2Wql8K7DR4aIrKmqLC4P7r43P8Vmj0wWtRz4IRqBpK389WykB7gv6Q7E3BeDzazB55url-zO7C0fh2mF2OQhBM1uF0EPNEgooGkZYMEpbIgdSccRAw0UpFKJJE8oTTWANlIp5wJZMUmQQEmoLokbN17sLZlwZ9nZeFV2gMVGgbn7MoTZlgEeeter5WlbPeO5zmC1eU4FY5o_lPx_m249Y92cQ2kxL11vwrtRVO1wIon89t46r2y3-CvgGHC4Ur</recordid><startdate>20131018</startdate><enddate>20131018</enddate><creator>Li, Gang</creator><creator>Jia, Chunqi</creator><creator>Sun, Kai</creator><general>American Chemical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20131018</creationdate><title>Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines</title><author>Li, Gang ; Jia, Chunqi ; Sun, Kai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a315t-f76285ac474d51a818575d212a3abdcc4e388528206da0136b2c589e15aea09a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Gang</creatorcontrib><creatorcontrib>Jia, Chunqi</creatorcontrib><creatorcontrib>Sun, Kai</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Organic letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Gang</au><au>Jia, Chunqi</au><au>Sun, Kai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines</atitle><jtitle>Organic letters</jtitle><addtitle>Org. Lett</addtitle><date>2013-10-18</date><risdate>2013</risdate><volume>15</volume><issue>20</issue><spage>5198</spage><epage>5201</epage><pages>5198-5201</pages><issn>1523-7060</issn><eissn>1523-7052</eissn><abstract>C–H, N–H dehydrogenative coupling of quinoline N-oxides with lactams/cyclamines has been achieved in the presence of the Cu(OAc)2 catalyst to give good to excellent yields. This study provides a new strategy for the construction of a 2-aminoquinoline skeleton via direct functionalization of aryl C–H bonds.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>24093556</pmid><doi>10.1021/ol402324v</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1523-7060
ispartof Organic letters, 2013-10, Vol.15 (20), p.5198-5201
issn 1523-7060
1523-7052
language eng
recordid cdi_proquest_miscellaneous_1499131422
source ACS Publications
title Copper-Catalyzed Intermolecular Dehydrogenative Amidation/Amination of Quinoline N‑Oxides with Lactams/Cyclamines
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T00%3A32%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Copper-Catalyzed%20Intermolecular%20Dehydrogenative%20Amidation/Amination%20of%20Quinoline%20N%E2%80%91Oxides%20with%20Lactams/Cyclamines&rft.jtitle=Organic%20letters&rft.au=Li,%20Gang&rft.date=2013-10-18&rft.volume=15&rft.issue=20&rft.spage=5198&rft.epage=5201&rft.pages=5198-5201&rft.issn=1523-7060&rft.eissn=1523-7052&rft_id=info:doi/10.1021/ol402324v&rft_dat=%3Cproquest_cross%3E1499131422%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1499131422&rft_id=info:pmid/24093556&rfr_iscdi=true