Mathematical and biostatistical methods for designing and analyzing complex chemical interactions

In this presentation, statistical methods for designing and analyzing experiments evaluating a mixture of drugs/chemicals are discussed. These methods are promising in that they are not limited by the number of interacting agents in the combination. Several examples are given and a discussion of the...

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Veröffentlicht in:Fundamental and applied toxicology 1988-05, Vol.10 (4), p.590-595
Hauptverfasser: Carter, W.H., Carchman, R.A.
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container_title Fundamental and applied toxicology
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creator Carter, W.H.
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description In this presentation, statistical methods for designing and analyzing experiments evaluating a mixture of drugs/chemicals are discussed. These methods are promising in that they are not limited by the number of interacting agents in the combination. Several examples are given and a discussion of the results follows.
doi_str_mv 10.1016/0272-0590(88)90185-6
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subjects Altretamine - toxicity
Animals
Biological and medical sciences
Cisplatin - toxicity
Drug-Related Side Effects and Adverse Reactions
Fluorouracil - toxicity
General aspects. Methods
Medical sciences
Mice
Mice, Inbred Strains
Models, Chemical
Razoxane
Sister Chromatid Exchange - drug effects
Statistics as Topic
Toxicology
title Mathematical and biostatistical methods for designing and analyzing complex chemical interactions
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