Mathematical and biostatistical methods for designing and analyzing complex chemical interactions

In this presentation, statistical methods for designing and analyzing experiments evaluating a mixture of drugs/chemicals are discussed. These methods are promising in that they are not limited by the number of interacting agents in the combination. Several examples are given and a discussion of the...

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Veröffentlicht in:	Fundamental and applied toxicology 1988-05, Vol.10 (4), p.590-595
Hauptverfasser:	Carter, W.H., Carchman, R.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Altretamine - toxicity Animals Biological and medical sciences Cisplatin - toxicity Drug-Related Side Effects and Adverse Reactions Fluorouracil - toxicity General aspects. Methods Medical sciences Mice Mice, Inbred Strains Models, Chemical Razoxane Sister Chromatid Exchange - drug effects Statistics as Topic Toxicology
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Beschreibung
Zusammenfassung:	In this presentation, statistical methods for designing and analyzing experiments evaluating a mixture of drugs/chemicals are discussed. These methods are promising in that they are not limited by the number of interacting agents in the combination. Several examples are given and a discussion of the results follows.
ISSN:	0272-0590 1095-6832
DOI:	10.1016/0272-0590(88)90185-6