Asymmetric-Catalysed Preparation and Stereochemistry of (R,R)-,(S,R)-(6-Fluoro-2-Chromanyl)-1,2-Ethanediol

Asymmetric-Catalysed Preparation and Stereochemistry of (R,R)-,(S,R)-(6-Fluoro-2-Chromanyl)-1,2-Ethanediol

(R,R)-,(S,R)-1-(6-fluoro-2-chromanyl)-1,2-ethanediol 1a/1b were prepared by hydrolytic kinetic resolution (HKR) of terminal racemic epoxides using (R,R)-SalenCo(OAc) as a catalyst. Their configurations were established by comparison with two authentic samples by HPLC.

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Veröffentlicht in:Journal of chemical research 2007-09, Vol.2007 (9), p.506-508
Hauptverfasser: Yang, Yun-Xu, Liu, Shi-Xiang
Format: Artikel
Sprache:eng
Schlagworte:
Asymmetry
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Beschreibung
Zusammenfassung:(R,R)-,(S,R)-1-(6-fluoro-2-chromanyl)-1,2-ethanediol 1a/1b were prepared by hydrolytic kinetic resolution (HKR) of terminal racemic epoxides using (R,R)-SalenCo(OAc) as a catalyst. Their configurations were established by comparison with two authentic samples by HPLC.
ISSN:1747-5198
2047-6507
DOI:10.3184/030823407X240908