A practical synthesis of chiral 3-aryloxy-1,2-propanediols
Chiral 3-aryloxy-1,2-propanediols (1-5) of >96 % ee were obtained in high yield by the nucleophilic addition of substituted phenols to chiral glycidol in the presence of piperidine hydrochloride as catalyst.
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| Veröffentlicht in: | Journal of chemical research 2005-01, Vol.2005 (1), p.41-42 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | Chiral 3-aryloxy-1,2-propanediols (1-5) of >96 % ee were obtained in high yield by the nucleophilic addition of substituted phenols to chiral glycidol in the presence of piperidine hydrochloride as catalyst. |
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| ISSN: | 1747-5198 2047-6507 |
| DOI: | 10.3184/0308234053431112 |