Microwave-promoted synthesis of ?-hydroxyesters by the Reformatsky reaction in the absence of solvent
A microwave-promoted Reformatsky reaction of aldehydes and ketones with ethyl bromoacetate, in the absence of solvent, using activated zinc metal and solid NH4Cl afforded the corresponding ?-hydroxyesters in good to excellent yields.
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| Veröffentlicht in: | Journal of chemical research 2003-06, Vol.2003 (6), p.374-376 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A microwave-promoted Reformatsky reaction of aldehydes and ketones with ethyl bromoacetate, in the absence of solvent, using activated zinc metal and solid NH4Cl afforded the corresponding ?-hydroxyesters in good to excellent yields. |
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| ISSN: | 1747-5198 2047-6507 |
| DOI: | 10.3184/030823403103174209 |