Theoretical studies of cyclic adenosine monophosphate dependent protein kinase: native enzyme and ground-state and transition-state analogues

The mechanisms of phosphoryl transfer enzymes have garnered considerable attention. Cyclic AMP-dependent protein kinase (cAPK) catalyzes the transfer of the γ phosphoryl group of ATP to the serine hydroxyl group of a peptide chain. Metal-containing fluoro species have been used as transition-state a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2014-02, Vol.43 (8), p.3039-3043
Hauptverfasser:	Leigh, Katherine N, Webster, Charles Edwin
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Catalytic Domain Crystallography, X-Ray Cyclic AMP-Dependent Protein Kinases - chemistry Cyclic AMP-Dependent Protein Kinases - metabolism Fluorides - chemistry Magnesium Compounds - chemistry Magnetic Resonance Spectroscopy Models, Theoretical Quantum Theory Thermodynamics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!