Predictors of Acute and Persisting Ischemic Brain Lesions in Patients Randomized to Carotid Stenting or Endarterectomy

We investigated predictors for acute and persisting periprocedural ischemic brain lesions among patients with symptomatic carotid stenosis randomized to stenting or endarterectomy in the International Carotid Stenting Study. We assessed acute lesions on diffusion-weighted imaging 1 to 3 days after t...

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Veröffentlicht in:	Stroke (1970) 2014-02, Vol.45 (2), p.591-594
Hauptverfasser:	ROSTAMZADEH, Ayda, ZUMBRUNN, Thomas, ENGELTER, Stefan T, BONATI, Leo H, JONGEN, Lisa M, NEDERKOORN, Paul J, MACDONALD, Sumaira, LYRER, Philippe A, KAPPELLE, L. Jaap, MALI, Willem P. Th. M, BROWN, Martin M, VAN DER WORP, H. Bart
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Biological and medical sciences Blood and lymphatic vessels Brain Ischemia - epidemiology Cardiology. Vascular system Carotid Arteries - surgery Carotid Stenosis - surgery Confidence Intervals Diffusion Magnetic Resonance Imaging Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Endarterectomy, Carotid - statistics & numerical data Female Follow-Up Studies Humans Hypertension - complications Image Processing, Computer-Assisted Male Medical sciences Neurology Neurosurgery Predictive Value of Tests Regression Analysis Risk Assessment Risk Factors Sex Characteristics Skull, brain, vascular surgery Stents - statistics & numerical data Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Vascular diseases and vascular malformations of the nervous system
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Zusammenfassung:	We investigated predictors for acute and persisting periprocedural ischemic brain lesions among patients with symptomatic carotid stenosis randomized to stenting or endarterectomy in the International Carotid Stenting Study. We assessed acute lesions on diffusion-weighted imaging 1 to 3 days after treatment in 124 stenting and 107 endarterectomy patients and lesions persisting on fluid-attenuated inversion recovery after 1 month in 86 and 75 patients, respectively. Stenting patients had more acute (relative risk, 8.8; 95% confidence interval, 4.4-17.5; P
ISSN:	0039-2499 1524-4628
DOI:	10.1161/STROKEAHA.113.003605