Physical training prevents oxidative stress in L-NAME-induced hypertension rats

The present study investigated the effects of a 6‐week swimming training on blood pressure, nitric oxide (NO) levels and oxidative stress parameters such as protein and lipid oxidation, antioxidant enzyme activity and endogenous non‐enzymatic antioxidant content in kidney and circulating fluids, as...

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Veröffentlicht in:Cell biochemistry and function 2013-03, Vol.31 (2), p.136-151
Hauptverfasser: Cardoso, Andréia Machado, Martins, Caroline Curry, Fiorin, Fernando da Silva, Schmatz, Roberta, Abdalla, Fátima Husein, Gutierres, Jessié, Zanini, Daniela, Fiorenza, Amanda Maino, Stefanello, Naiara, Serres, Jonas Daci da Silva, Carvalho, Fabiano, Castro, Verônica Paiva, Mazzanti, Cinthia Melazzo, Royes, Luiz Fernando Freire, Belló-Klein, Adriane, Goularte, Jeferson Ferraz, Morsch, Vera Maria, Bagatini, Margarete Dulce, Schetinger, Maria Rosa Chitolina
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Sprache:eng
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Zusammenfassung:The present study investigated the effects of a 6‐week swimming training on blood pressure, nitric oxide (NO) levels and oxidative stress parameters such as protein and lipid oxidation, antioxidant enzyme activity and endogenous non‐enzymatic antioxidant content in kidney and circulating fluids, as well as on serum biochemical parameters (cholesterol, triglycerides, urea and creatinine) from Nω‐nitro‐L‐arginine methyl ester hydrochloride (L‐NAME)‐induced hypertension treated rats. Animals were divided into four groups (n = 10): Control, Exercise, L‐NAME and Exercise L‐NAME. Results showed that exercise prevented a decrease in NO levels in hypertensive rats (P 
ISSN:0263-6484
1099-0844
DOI:10.1002/cbf.2868