Pregnancy loss managed by cervical dilatation and curettage increases the risk of spontaneous preterm birth
STUDY QUESTION Do women with a previous miscarriage or termination of pregnancy have an increased risk of spontaneous preterm birth and is this related to previous cervical dilatation and curettage? SUMMARY ANSWER A single previous pregnancy loss (termination or miscarriage) managed by cervical dila...
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Veröffentlicht in: | Human reproduction (Oxford) 2013-12, Vol.28 (12), p.3197-3206 |
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Sprache: | eng |
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Zusammenfassung: | STUDY QUESTION
Do women with a previous miscarriage or termination of pregnancy have an increased risk of spontaneous preterm birth and is this related to previous cervical dilatation and curettage?
SUMMARY ANSWER
A single previous pregnancy loss (termination or miscarriage) managed by cervical dilatation and curettage is associated with a greater risk of SpPTB.
WHAT IS KNOWN ALREADY
Miscarriage affects ∼20% of pregnancies and as many as a further 20% of pregnancies undergo termination.
STUDY DESIGN, SIZE, DURATION
We utilized data from 5575 healthy nulliparous women with singleton pregnancies recruited to the Screening for Pregnancy Endpoints (SCOPE) study, a prospective cohort study performed between November 2004 and January 2011.
PARTICIPANTS/MATERIALS, SETTING, METHODS
The primary outcome was spontaneous preterm birth (defined as spontaneous preterm labour or preterm premature rupture of membranes (PPROM) resulting in preterm birth |
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ISSN: | 0268-1161 1460-2350 |
DOI: | 10.1093/humrep/det332 |