Chitosan/nano-hydroxyapatite composite electret membranes enhance cell proliferation and osteoblastic expression in vitro

Chitosan/nano-hydroxyapatite composite electret membranes enhance cell proliferation and osteoblastic expression in vitro

Chitosan/nano-hydroxyapatite membranes with negative charges were fabricated by grid-controlled constant voltage corona charging, and the charged membranes were investigated for cell biocompatibility and osteoinduction. The osteoblasts on the chitosan/nano-hydroxyapatite composite electret membranes...

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Veröffentlicht in:Journal of bioactive and compatible polymers 2014-01, Vol.29 (1), p.3-14
Hauptverfasser: Qu, Yili, Ao, Danting, Wang, Ping, Wang, Yanying, Kong, Xiangli, Man, Yi
Format: Artikel
Sprache:eng
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Applied sciences
Composites
Exact sciences and technology
Forms of application and semi-finished materials
Laminates
Polymer industry, paints, wood
Technology of polymers
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container_issue 1
container_start_page 3
container_title Journal of bioactive and compatible polymers
container_volume 29
creator Qu, Yili
Ao, Danting
Wang, Ping
Wang, Yanying
Kong, Xiangli
Man, Yi
description Chitosan/nano-hydroxyapatite membranes with negative charges were fabricated by grid-controlled constant voltage corona charging, and the charged membranes were investigated for cell biocompatibility and osteoinduction. The osteoblasts on the chitosan/nano-hydroxyapatite composite electret membranes significantly enhanced the adhesion, proliferation, and differentiation capacity compared to the uncharged group. This study not only provides evidence for the potential clinical application of our novel membranes but also could be used as a strategy for chitosan/nano-hydroxyapatite scaffolds.
doi_str_mv 10.1177/0883911513513094
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subjects Applied sciences
Composites
Exact sciences and technology
Forms of application and semi-finished materials
Laminates
Polymer industry, paints, wood
Technology of polymers
title Chitosan/nano-hydroxyapatite composite electret membranes enhance cell proliferation and osteoblastic expression in vitro
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