Decomposition of number of life years lost according to causes of death

We study the competing risks model and show that the cause j cumulative incidence function integrated from 0 to τ has a natural interpretation as the expected number of life years lost due to cause j before time τ. This is analogous to the τ‐restricted mean lifetime, which is the survival function i...

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Veröffentlicht in:Statistics in medicine 2013-12, Vol.32 (30), p.5278-5285
1. Verfasser: Andersen, P. K.
Format: Artikel
Sprache:eng
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Zusammenfassung:We study the competing risks model and show that the cause j cumulative incidence function integrated from 0 to τ has a natural interpretation as the expected number of life years lost due to cause j before time τ. This is analogous to the τ‐restricted mean lifetime, which is the survival function integrated from 0 to τ. It is discussed how the number of years lost may be related to subject‐specific explanatory variables in a regression model based on pseudo‐observations, and the method is exemplified using data from a bone marrow transplantation study. Finally, inclusion of standard mortality rates is discussed. Copyright © 2013 John Wiley & Sons, Ltd.
ISSN:0277-6715
1097-0258
DOI:10.1002/sim.5903