The Pivotal Role of FDG-PET/CT in Modern Medicine

The technology behind positron emission tomography (PET) and the most widely used tracer, 2-deoxy-2-[18F]fluoro-D-glucose (FDG), were both conceived in the 1970s, but the latest decade has witnessed a rapid emergence of FDG-PET as an effective imaging technique. This is not least due to the emergenc...

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Veröffentlicht in:	Academic radiology 2014-02, Vol.21 (2), p.232-249
Hauptverfasser:	Hess, Søren, MD, Blomberg, Björn A., MD, MSc, Zhu, Hongyun June, MD, Høilund-Carlsen, Poul Flemming, MD, DMSc, Alavi, Abass, MD, DSc (hon.), PhD (hon.)
Format:	Artikel
Sprache:	eng
Schlagworte:	2-deoxy-2-[18F]fluoro-D-glucose FDG Fluorodeoxyglucose F18 - pharmacokinetics Humans molecular imaging Molecular Imaging - methods Multimodal Imaging - methods PET/CT Positron emission tomography/computed tomography Positron-Emission Tomography - methods Radiology Radiopharmaceuticals - pharmacokinetics Tomography, X-Ray Computed - methods
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Zusammenfassung:	The technology behind positron emission tomography (PET) and the most widely used tracer, 2-deoxy-2-[18F]fluoro-D-glucose (FDG), were both conceived in the 1970s, but the latest decade has witnessed a rapid emergence of FDG-PET as an effective imaging technique. This is not least due to the emergence of hybrid scanners combining PET with computed tomography (PET/CT). Molecular imaging has enormous potential for advancing biological research and patient care, and FDG-PET/CT is currently the most widely used technology in this domain. In this review, we discuss contemporary applications of FDG-PET and FDG-PET/CT as well as novel developments in quantification and potential future indications including the emerging new modality PET/magnetic resonance imaging.
ISSN:	1076-6332 1878-4046
DOI:	10.1016/j.acra.2013.11.002