Synthesis of deuterated and tritiated gossypol
We report here the synthesis of deuterated and tritiated gossypol by exchange with labelleled water using trifluoroacetic acid as the catalyst. In the case of D2O in tetrahydrofuran, the exchange is complete in 45 minutes at 75°C as determined by a 1H‐NMR spectrum.
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| Veröffentlicht in: | Journal of labelled compounds & radiopharmaceuticals 1987-06, Vol.24 (6), p.741-743 |
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| container_end_page | 743 |
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| container_issue | 6 |
| container_start_page | 741 |
| container_title | Journal of labelled compounds & radiopharmaceuticals |
| container_volume | 24 |
| creator | Stipanovic, Robert D. Williams, Howard J. Muehleisen, David P. Plapp Jr, F. W. |
| description | We report here the synthesis of deuterated and tritiated gossypol by exchange with labelleled water using trifluoroacetic acid as the catalyst. In the case of D2O in tetrahydrofuran, the exchange is complete in 45 minutes at 75°C as determined by a 1H‐NMR spectrum. |
| doi_str_mv | 10.1002/jlcr.2580240616 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0362-4803 |
| ispartof | Journal of labelled compounds & radiopharmaceuticals, 1987-06, Vol.24 (6), p.741-743 |
| issn | 0362-4803 1099-1344 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_14908445 |
| source | Wiley Journals |
| subjects | acid catalyzed exchange deuterium Gossypol tritium |
| title | Synthesis of deuterated and tritiated gossypol |
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