2‑Hydroxy-1,10-phenanthroline vs 1,10-Phenanthroline: Significant Ligand Acceleration Effects in the Palladium-Catalyzed Oxidative Heck Reaction of Arenes

2‑Hydroxy-1,10-phenanthroline vs 1,10-Phenanthroline: Significant Ligand Acceleration Effects in the Palladium-Catalyzed Oxidative Heck Reaction of Arenes

A series of bidentate monoanionic nitrogen ligands were designed and applied in the Pd-catalyzed oxidative Heck reaction of arenes with alkenes. Significant ligand-accelerated effects were observed, and direct C–H functionalized products were formed in high yields with meta-selectivity.

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Veröffentlicht in:Organic letters 2014-01, Vol.16 (2), p.500-503
Hauptverfasser: Ying, Cheng-Hao, Yan, Shao-Bai, Duan, Wei-Liang
Format: Artikel
Sprache:eng
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Zusammenfassung:A series of bidentate monoanionic nitrogen ligands were designed and applied in the Pd-catalyzed oxidative Heck reaction of arenes with alkenes. Significant ligand-accelerated effects were observed, and direct C–H functionalized products were formed in high yields with meta-selectivity.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol4033804