Guidelines for optimizing design and analysis of clinical studies of nutrient effects
Presented here is a system to standardize clinical studies of nutrient effects, using nutrient‐specific physiological criteria. These guidelines are based mainly on analysis of the typical sigmoid curve of biological response to nutrients and are intended for design, interpretation, and pooling of s...
Gespeichert in:
| Veröffentlicht in: | Nutrition reviews 2014-01, Vol.72 (1), p.48-54 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 54 |
|---|---|
| container_issue | 1 |
| container_start_page | 48 |
| container_title | Nutrition reviews |
| container_volume | 72 |
| creator | Heaney, Robert P |
| description | Presented here is a system to standardize clinical studies of nutrient effects, using nutrient‐specific physiological criteria. These guidelines are based mainly on analysis of the typical sigmoid curve of biological response to nutrients and are intended for design, interpretation, and pooling of studies of nutrient effects. Five rules have been articulated for individual studies of nutrients, and six for systematic reviews and/or meta‐analyses. |
| doi_str_mv | 10.1111/nure.12090 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1490759766</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3183050201</sourcerecordid><originalsourceid>FETCH-LOGICAL-p2110-406bae968cfc5243897965ed2d788c1efd6e2c21092c32eb2fb2ca9d83df861c3</originalsourceid><addsrcrecordid>eNpd0ctKAzEUBuAgiq3VjQ8gA27cTM1lJpellFoFURC7HmaSk5IylzqZIPXpTS-6MBBySD5CTn6Ergmekjju29DDlFCs8AkaE5GzNJNSnKIxxlSlnGdshC68X2OMCVXsHI1oxhgmjI_RchGcgdq14BPb9Um3GVzjvl27Sgx4t2qTsjVxlvXWO590NtERO13WiR-CcbDfa8PQO2iHBKwFPfhLdGbL2sPVcZ2g5eP8Y_aUvrwtnmcPL-mGEoLTDPOqBMWltjqPb5JKKJ6DoUZIqQlYw4FqSrCimlGoqK2oLpWRzFjJiWYTdHe4d9N3nwH8UDTOa6jrsoUu-IJkCotcCc4jvf1H113oY187JYSQ0eCobo4qVA2YYtO7puy3xe-HRUAO4MvVsP07J7jYRVHsoij2URSvy_f5vmI_4nB78g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1477786630</pqid></control><display><type>article</type><title>Guidelines for optimizing design and analysis of clinical studies of nutrient effects</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Heaney, Robert P</creator><creatorcontrib>Heaney, Robert P</creatorcontrib><description>Presented here is a system to standardize clinical studies of nutrient effects, using nutrient‐specific physiological criteria. These guidelines are based mainly on analysis of the typical sigmoid curve of biological response to nutrients and are intended for design, interpretation, and pooling of studies of nutrient effects. Five rules have been articulated for individual studies of nutrients, and six for systematic reviews and/or meta‐analyses.</description><identifier>ISSN: 0029-6643</identifier><identifier>EISSN: 1753-4887</identifier><identifier>DOI: 10.1111/nure.12090</identifier><identifier>PMID: 24330136</identifier><identifier>CODEN: NUREA8</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Clinical Protocols - standards ; clinical studies ; Clinical trials ; Design optimization ; Evidence-Based Medicine ; Guidelines as Topic ; Humans ; Meta-analysis ; nutrient effects ; Nutrition ; Physiology ; Research Design ; Review Literature as Topic ; sigmoid curve ; study design ; Systematic review</subject><ispartof>Nutrition reviews, 2014-01, Vol.72 (1), p.48-54</ispartof><rights>2013 International Life Sciences Institute</rights><rights>2013 International Life Sciences Institute.</rights><rights>Copyright International Life Sciences Institute Jan 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fnure.12090$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fnure.12090$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24330136$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Heaney, Robert P</creatorcontrib><title>Guidelines for optimizing design and analysis of clinical studies of nutrient effects</title><title>Nutrition reviews</title><addtitle>Nutr Rev</addtitle><description>Presented here is a system to standardize clinical studies of nutrient effects, using nutrient‐specific physiological criteria. These guidelines are based mainly on analysis of the typical sigmoid curve of biological response to nutrients and are intended for design, interpretation, and pooling of studies of nutrient effects. Five rules have been articulated for individual studies of nutrients, and six for systematic reviews and/or meta‐analyses.</description><subject>Clinical Protocols - standards</subject><subject>clinical studies</subject><subject>Clinical trials</subject><subject>Design optimization</subject><subject>Evidence-Based Medicine</subject><subject>Guidelines as Topic</subject><subject>Humans</subject><subject>Meta-analysis</subject><subject>nutrient effects</subject><subject>Nutrition</subject><subject>Physiology</subject><subject>Research Design</subject><subject>Review Literature as Topic</subject><subject>sigmoid curve</subject><subject>study design</subject><subject>Systematic review</subject><issn>0029-6643</issn><issn>1753-4887</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0ctKAzEUBuAgiq3VjQ8gA27cTM1lJpellFoFURC7HmaSk5IylzqZIPXpTS-6MBBySD5CTn6Ergmekjju29DDlFCs8AkaE5GzNJNSnKIxxlSlnGdshC68X2OMCVXsHI1oxhgmjI_RchGcgdq14BPb9Um3GVzjvl27Sgx4t2qTsjVxlvXWO590NtERO13WiR-CcbDfa8PQO2iHBKwFPfhLdGbL2sPVcZ2g5eP8Y_aUvrwtnmcPL-mGEoLTDPOqBMWltjqPb5JKKJ6DoUZIqQlYw4FqSrCimlGoqK2oLpWRzFjJiWYTdHe4d9N3nwH8UDTOa6jrsoUu-IJkCotcCc4jvf1H113oY187JYSQ0eCobo4qVA2YYtO7puy3xe-HRUAO4MvVsP07J7jYRVHsoij2URSvy_f5vmI_4nB78g</recordid><startdate>201401</startdate><enddate>201401</enddate><creator>Heaney, Robert P</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201401</creationdate><title>Guidelines for optimizing design and analysis of clinical studies of nutrient effects</title><author>Heaney, Robert P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2110-406bae968cfc5243897965ed2d788c1efd6e2c21092c32eb2fb2ca9d83df861c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Clinical Protocols - standards</topic><topic>clinical studies</topic><topic>Clinical trials</topic><topic>Design optimization</topic><topic>Evidence-Based Medicine</topic><topic>Guidelines as Topic</topic><topic>Humans</topic><topic>Meta-analysis</topic><topic>nutrient effects</topic><topic>Nutrition</topic><topic>Physiology</topic><topic>Research Design</topic><topic>Review Literature as Topic</topic><topic>sigmoid curve</topic><topic>study design</topic><topic>Systematic review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Heaney, Robert P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Nutrition reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Heaney, Robert P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Guidelines for optimizing design and analysis of clinical studies of nutrient effects</atitle><jtitle>Nutrition reviews</jtitle><addtitle>Nutr Rev</addtitle><date>2014-01</date><risdate>2014</risdate><volume>72</volume><issue>1</issue><spage>48</spage><epage>54</epage><pages>48-54</pages><issn>0029-6643</issn><eissn>1753-4887</eissn><coden>NUREA8</coden><abstract>Presented here is a system to standardize clinical studies of nutrient effects, using nutrient‐specific physiological criteria. These guidelines are based mainly on analysis of the typical sigmoid curve of biological response to nutrients and are intended for design, interpretation, and pooling of studies of nutrient effects. Five rules have been articulated for individual studies of nutrients, and six for systematic reviews and/or meta‐analyses.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>24330136</pmid><doi>10.1111/nure.12090</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0029-6643 |
| ispartof | Nutrition reviews, 2014-01, Vol.72 (1), p.48-54 |
| issn | 0029-6643 1753-4887 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1490759766 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Clinical Protocols - standards clinical studies Clinical trials Design optimization Evidence-Based Medicine Guidelines as Topic Humans Meta-analysis nutrient effects Nutrition Physiology Research Design Review Literature as Topic sigmoid curve study design Systematic review |
| title | Guidelines for optimizing design and analysis of clinical studies of nutrient effects |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T02%3A07%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Guidelines%20for%20optimizing%20design%20and%20analysis%20of%20clinical%20studies%20of%20nutrient%20effects&rft.jtitle=Nutrition%20reviews&rft.au=Heaney,%20Robert%20P&rft.date=2014-01&rft.volume=72&rft.issue=1&rft.spage=48&rft.epage=54&rft.pages=48-54&rft.issn=0029-6643&rft.eissn=1753-4887&rft.coden=NUREA8&rft_id=info:doi/10.1111/nure.12090&rft_dat=%3Cproquest_pubme%3E3183050201%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1477786630&rft_id=info:pmid/24330136&rfr_iscdi=true |