Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids

Facile synthesis of ultra-small hybrid silica spheres for enhanced penetration in 3D glioma spheroids

A facile approach has been developed to prepare ultra-small hybrid silica spheres with a diameter of ∼10 nm, which show highly enhanced penetration ability in 3D glioma spheroids compared to conventional mesoporous silica nanoparticles.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2014-01, Vol.50 (13), p.1527-1529
Hauptverfasser: Yu, Meihua, Karmakar, Surajit, Yang, Jie, Zhang, Hongwei, Yang, Yannan, Thorn, Peter, Yu, Chengzhong
Format: Artikel
Sprache:eng
Schlagworte:
Brain - cytology
Brain - metabolism
Brain Neoplasms - diagnosis
Glioma - diagnosis
Glioma - metabolism
Humans
Nanoparticles - analysis
Nanoparticles - metabolism
Particle Size
Permeability
Porosity
Silicon Dioxide - analysis
Silicon Dioxide - metabolism
Spheroids, Cellular - metabolism
Tumor Cells, Cultured
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A facile approach has been developed to prepare ultra-small hybrid silica spheres with a diameter of ∼10 nm, which show highly enhanced penetration ability in 3D glioma spheroids compared to conventional mesoporous silica nanoparticles.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc48416e