A review of maternally inherited diabetes and deafness

Maternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of c...

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Veröffentlicht in:Frontiers in bioscience 2014-01, Vol.19 (5), p.777-782
Hauptverfasser: Li, Hui-Zhen, Li, Rui-Yu, Li, Meng
Format: Artikel
Sprache:eng
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Zusammenfassung:Maternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of clinical and genetic diagnosis of MIDD; outlines the advances of the clinical management of these patients and their families.
ISSN:1093-9946
2768-6698
1093-4715
DOI:10.2741/4244