Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy
Dose parameters of the Radachlorin photosensitizer were tested under conditions of pulsed and continuous laser excitation with a Lakhta-Milon laser. The photodynamic effect was tested using erythrocyte suspension in saline. The experimental and theoretical results were shown to correlate qualitative...
Gespeichert in:
| Veröffentlicht in: | Biomedical engineering 2013-03, Vol.46 (6), p.250-254 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 254 |
|---|---|
| container_issue | 6 |
| container_start_page | 250 |
| container_title | Biomedical engineering |
| container_volume | 46 |
| creator | Zhorina, L. V. Zmievskoy, G. N. Semchuk, I. P. Filatov, V. V. |
| description | Dose parameters of the Radachlorin photosensitizer were tested under conditions of pulsed and continuous laser excitation with a Lakhta-Milon laser. The photodynamic effect was tested using erythrocyte suspension in saline. The experimental and theoretical results were shown to correlate qualitatively. Comparative analysis demonstrated that the continuous exposure mode provided a higher rate of death of sensitized cells. It was shown that at certain parameters of pulse radiation there was no threshold dose. |
| doi_str_mv | 10.1007/s10527-013-9317-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1475553606</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1475553606</sourcerecordid><originalsourceid>FETCH-LOGICAL-c216x-f206d334388be39bfecc97fba34256510fdd81f21e0f2e0570f09546d3ec65c73</originalsourceid><addsrcrecordid>eNp1kE9LAzEQxYMoWKsfwNuCFy_RSbLZ7B6l-A8KFqnnkGYndkt3U5MtdL-9WepBBGFgmJnfGx6PkGsGdwxA3UcGkisKTNBKMEUPJ2TCpBK05LI4JRMAKKgQVXlOLmLcpFGWJZ-QxaNzaPvMu2zZtJgtTDAt9hjiuJqbiCF7N3Vj-sZ3WarEN9bYYTwv1r739dCZtrHZco3B7IZLcubMNuLVT5-Sj6fH5eyFzt-eX2cPc2o5Kw7UcShqIXJRlisU1SqZsJVyKyPyZFgycHVdMscZguMIUoGDSuZJg7aQVokpuT3-3QX_tcfY67aJFrdb06HfR81yJaUUBRQJvfmDbvw-dMldogouKlkpmSh2pGzwMQZ0ehea1oRBM9BjxvqYsU4Z6zFjfUgaftTExHafGH59_lf0Dd0AfhU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1462395975</pqid></control><display><type>article</type><title>Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy</title><source>Springer Nature - Complete Springer Journals</source><creator>Zhorina, L. V. ; Zmievskoy, G. N. ; Semchuk, I. P. ; Filatov, V. V.</creator><creatorcontrib>Zhorina, L. V. ; Zmievskoy, G. N. ; Semchuk, I. P. ; Filatov, V. V.</creatorcontrib><description>Dose parameters of the Radachlorin photosensitizer were tested under conditions of pulsed and continuous laser excitation with a Lakhta-Milon laser. The photodynamic effect was tested using erythrocyte suspension in saline. The experimental and theoretical results were shown to correlate qualitatively. Comparative analysis demonstrated that the continuous exposure mode provided a higher rate of death of sensitized cells. It was shown that at certain parameters of pulse radiation there was no threshold dose.</description><identifier>ISSN: 0006-3398</identifier><identifier>EISSN: 1573-8256</identifier><identifier>DOI: 10.1007/s10527-013-9317-x</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Biomaterials ; Biomedical engineering ; Biomedical Engineering and Bioengineering ; Cell death ; Comparative analysis ; Engineering ; Laser radiation ; Lasers ; Parameters ; Photodynamic therapy ; Radiation</subject><ispartof>Biomedical engineering, 2013-03, Vol.46 (6), p.250-254</ispartof><rights>Springer Science+Business Media New York 2013</rights><rights>Springer Science+Business Media New York 2013.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c216x-f206d334388be39bfecc97fba34256510fdd81f21e0f2e0570f09546d3ec65c73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10527-013-9317-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10527-013-9317-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids></links><search><creatorcontrib>Zhorina, L. V.</creatorcontrib><creatorcontrib>Zmievskoy, G. N.</creatorcontrib><creatorcontrib>Semchuk, I. P.</creatorcontrib><creatorcontrib>Filatov, V. V.</creatorcontrib><title>Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy</title><title>Biomedical engineering</title><addtitle>Biomed Eng</addtitle><description>Dose parameters of the Radachlorin photosensitizer were tested under conditions of pulsed and continuous laser excitation with a Lakhta-Milon laser. The photodynamic effect was tested using erythrocyte suspension in saline. The experimental and theoretical results were shown to correlate qualitatively. Comparative analysis demonstrated that the continuous exposure mode provided a higher rate of death of sensitized cells. It was shown that at certain parameters of pulse radiation there was no threshold dose.</description><subject>Biomaterials</subject><subject>Biomedical engineering</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Cell death</subject><subject>Comparative analysis</subject><subject>Engineering</subject><subject>Laser radiation</subject><subject>Lasers</subject><subject>Parameters</subject><subject>Photodynamic therapy</subject><subject>Radiation</subject><issn>0006-3398</issn><issn>1573-8256</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kE9LAzEQxYMoWKsfwNuCFy_RSbLZ7B6l-A8KFqnnkGYndkt3U5MtdL-9WepBBGFgmJnfGx6PkGsGdwxA3UcGkisKTNBKMEUPJ2TCpBK05LI4JRMAKKgQVXlOLmLcpFGWJZ-QxaNzaPvMu2zZtJgtTDAt9hjiuJqbiCF7N3Vj-sZ3WarEN9bYYTwv1r739dCZtrHZco3B7IZLcubMNuLVT5-Sj6fH5eyFzt-eX2cPc2o5Kw7UcShqIXJRlisU1SqZsJVyKyPyZFgycHVdMscZguMIUoGDSuZJg7aQVokpuT3-3QX_tcfY67aJFrdb06HfR81yJaUUBRQJvfmDbvw-dMldogouKlkpmSh2pGzwMQZ0ehea1oRBM9BjxvqYsU4Z6zFjfUgaftTExHafGH59_lf0Dd0AfhU</recordid><startdate>20130301</startdate><enddate>20130301</enddate><creator>Zhorina, L. V.</creator><creator>Zmievskoy, G. N.</creator><creator>Semchuk, I. P.</creator><creator>Filatov, V. V.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>L6V</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20130301</creationdate><title>Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy</title><author>Zhorina, L. V. ; Zmievskoy, G. N. ; Semchuk, I. P. ; Filatov, V. V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c216x-f206d334388be39bfecc97fba34256510fdd81f21e0f2e0570f09546d3ec65c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Biomaterials</topic><topic>Biomedical engineering</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Cell death</topic><topic>Comparative analysis</topic><topic>Engineering</topic><topic>Laser radiation</topic><topic>Lasers</topic><topic>Parameters</topic><topic>Photodynamic therapy</topic><topic>Radiation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhorina, L. V.</creatorcontrib><creatorcontrib>Zmievskoy, G. N.</creatorcontrib><creatorcontrib>Semchuk, I. P.</creatorcontrib><creatorcontrib>Filatov, V. V.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Biomedical engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhorina, L. V.</au><au>Zmievskoy, G. N.</au><au>Semchuk, I. P.</au><au>Filatov, V. V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy</atitle><jtitle>Biomedical engineering</jtitle><stitle>Biomed Eng</stitle><date>2013-03-01</date><risdate>2013</risdate><volume>46</volume><issue>6</issue><spage>250</spage><epage>254</epage><pages>250-254</pages><issn>0006-3398</issn><eissn>1573-8256</eissn><abstract>Dose parameters of the Radachlorin photosensitizer were tested under conditions of pulsed and continuous laser excitation with a Lakhta-Milon laser. The photodynamic effect was tested using erythrocyte suspension in saline. The experimental and theoretical results were shown to correlate qualitatively. Comparative analysis demonstrated that the continuous exposure mode provided a higher rate of death of sensitized cells. It was shown that at certain parameters of pulse radiation there was no threshold dose.</abstract><cop>Boston</cop><pub>Springer US</pub><doi>10.1007/s10527-013-9317-x</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-3398 |
| ispartof | Biomedical engineering, 2013-03, Vol.46 (6), p.250-254 |
| issn | 0006-3398 1573-8256 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1475553606 |
| source | Springer Nature - Complete Springer Journals |
| subjects | Biomaterials Biomedical engineering Biomedical Engineering and Bioengineering Cell death Comparative analysis Engineering Laser radiation Lasers Parameters Photodynamic therapy Radiation |
| title | Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T18%3A50%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20Time%20Parameters%20of%20Laser%20Radiation%20on%20Efficacy%20of%20Photodynamic%20Therapy&rft.jtitle=Biomedical%20engineering&rft.au=Zhorina,%20L.%20V.&rft.date=2013-03-01&rft.volume=46&rft.issue=6&rft.spage=250&rft.epage=254&rft.pages=250-254&rft.issn=0006-3398&rft.eissn=1573-8256&rft_id=info:doi/10.1007/s10527-013-9317-x&rft_dat=%3Cproquest_cross%3E1475553606%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1462395975&rft_id=info:pmid/&rfr_iscdi=true |