Effect of Time Parameters of Laser Radiation on Efficacy of Photodynamic Therapy

Dose parameters of the Radachlorin photosensitizer were tested under conditions of pulsed and continuous laser excitation with a Lakhta-Milon laser. The photodynamic effect was tested using erythrocyte suspension in saline. The experimental and theoretical results were shown to correlate qualitatively. Comparative analysis demonstrated that the continuous exposure mode provided a higher rate of death of sensitized cells. It was shown that at certain parameters of pulse radiation there was no threshold dose.