Isolation and characterization of a Streptomyces C5 mutant strain hyperproductive of extracellular protease

A pleiotropic streptomycete mutant was isolated that overproduced extracellular protease activity on azocasein, whereas the parent strain, Streptomyces C5, produced only negligible extracellular azocaseinase activity. Also unlike the parent strain, the mutant, designated C5-A13, was nonpigmented, an...

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Veröffentlicht in:	Biotechnology letters 1987-01, Vol.9 (9), p.605-610
Hauptverfasser:	Gibb, G.D, Dekleva, M.L, Lampel, J.S, Strohl, W.R
Format:	Artikel
Sprache:	eng
Schlagworte:	azocasein Biological and medical sciences Biology of microorganisms of confirmed or potential industrial interest Biotechnology carbon sources extracellular enzymes extracellular spaces Food industries Food microbiology Fundamental and applied biological sciences. Psychology isolation Mission oriented research mutants Physiology and metabolism proteinase proteinases strain differences Streptomyces
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Zusammenfassung:	A pleiotropic streptomycete mutant was isolated that overproduced extracellular protease activity on azocasein, whereas the parent strain, Streptomyces C5, produced only negligible extracellular azocaseinase activity. Also unlike the parent strain, the mutant, designated C5-A13, was nonpigmented, and was unable to sporulate or produce antibiotics.
ISSN:	0141-5492 1573-6776
DOI:	10.1007/BF01033195