The mediation of cyclic AMP in octopaminergic modulation at neuromuscular junctions of the mealworm, Tenebrio molitor

The possibility that there is mediation of cyclic AMP in the octopaminergic modulation of neuromuscular transmission was examined. Octopamine potentiated the amplitude of neurally-evoked excitatory junctional potentials (EJPs) at the neuromuscular junctions on the ventral longitudinal muscle of the...

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Veröffentlicht in:Zoological science 1987-06, Vol.4 (3), p.447-450
Hauptverfasser: HIDOH, O, FUKAMI, J.-I
Format: Artikel
Sprache:eng
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Zusammenfassung:The possibility that there is mediation of cyclic AMP in the octopaminergic modulation of neuromuscular transmission was examined. Octopamine potentiated the amplitude of neurally-evoked excitatory junctional potentials (EJPs) at the neuromuscular junctions on the ventral longitudinal muscle of the mealworm, Tenebrio molitor . The amplitude of EJPs was potentiated by these compounds when phosphodiesterase activity was inhibited. The results support the presynaptic mediation of cyclic AMP in octopaminergic modulation at neuromuscular junctions.
ISSN:0289-0003