Formation of pyrimidin-2-ylcyanamide and 2-aminopyrimidine in the reaction of aniline derivatives with cyanamide and dimethylamino-1-pyridyl-2-propenone

Substituted o - and p -nitroanilines and m -benzylaminoanilines in the reaction with cyanamide failed to yield the corresponding arylguanidines, and in the presence of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one formed 4-pyridyl-substituted pyrimidin-2-ylcyanamides and 2-amino-pyrimidines.

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Veröffentlicht in:Russian journal of organic chemistry 2011-08, Vol.47 (8), p.1222-1226
Hauptverfasser: Koroleva, E. V., Ignatovich, Zh. V., Ignatovich, S. V., Gusak, K. N.
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Sprache:eng
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Zusammenfassung:Substituted o - and p -nitroanilines and m -benzylaminoanilines in the reaction with cyanamide failed to yield the corresponding arylguanidines, and in the presence of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one formed 4-pyridyl-substituted pyrimidin-2-ylcyanamides and 2-amino-pyrimidines.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428011080173