Polymethylene derivatives of nucleic bases bearing Delta w-functional groups. VIII. Delta w-Oxo- Delta w-phenylalkylpyrimidines and -purines

Novel polymethylene derivatives of nucleic bases containing a phenylketo functional group at the Delta *w-position were synthesized by the alkylation of uracil, thymine, cytosine, hypoxanthine, adenine, and N-isobutyrylguanine with Delta *w-chloro-l-phenylalkan-1-ones and their physicochemical prope...

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Veröffentlicht in:Russian journal of bioorganic chemistry 2010-07, Vol.36 (4), p.477-487
Hauptverfasser: Komissarov, V V, Kritzyn, A M
Format: Artikel
Sprache:eng
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Zusammenfassung:Novel polymethylene derivatives of nucleic bases containing a phenylketo functional group at the Delta *w-position were synthesized by the alkylation of uracil, thymine, cytosine, hypoxanthine, adenine, and N-isobutyrylguanine with Delta *w-chloro-l-phenylalkan-1-ones and their physicochemical properties were studied.
ISSN:1068-1620
DOI:10.1134/S1068162010040060