The inhibitory effect of sleep deprivation on cell proliferation in the hippocampus of adult mice is eliminated by corticosterone clamp combined with interleukin-1 receptor 1 knockout

The inhibitory effect of sleep deprivation on cell proliferation in the hippocampus of adult mice is eliminated by corticosterone clamp combined with interleukin-1 receptor 1 knockout

Highlight • Rapid-eye-movement sleep deprivation inhibits cell proliferation in the adult mouse hippocampus via interleukin 1 signaling or elevated corticosterone.

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Bibliographische Detailangaben
Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2014-01, Vol.35, p.182-188
Hauptverfasser: Mueller, Anka D, Parfyonov, Maksim, Pavlovski, Ilia, Marchant, Elliott G, Mistlberger, Ralph E
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Animals
BrdU
Cell Proliferation
Corticosterone
Corticosterone - blood
Corticosterone - physiology
Hippocampus
Hippocampus - physiopathology
Interleukin-1-β
Ki67
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Neurogenesis
Psychiatry
Rapid-eye-movement sleep deprivation
Receptors, Interleukin-1 - genetics
Sleep Deprivation - physiopathology
Stress, Psychological - physiopathology
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Zusammenfassung:Highlight • Rapid-eye-movement sleep deprivation inhibits cell proliferation in the adult mouse hippocampus via interleukin 1 signaling or elevated corticosterone.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2013.10.001