Pharmacokinetics of 2,3,7,8-TCDD in man

A single dose of 1.14 ng of 3H-2,3,7,8-TCDD/kg bw, ingested by a human volunteer, was absorbed almost completely from the intestine (> 87 %). The resulting adipose tissue levels, measured 13 and 69 days after dosage were 3.09±0.05 and 2.85±0.28 ppt, respectively. The dioxin was cleared from the b...

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Veröffentlicht in:Chemosphere (Oxford) 1986, Vol.15 (9), p.1489-1494
Hauptverfasser: Poiger, H., Schlatter, C.
Format: Artikel
Sprache:eng
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Zusammenfassung:A single dose of 1.14 ng of 3H-2,3,7,8-TCDD/kg bw, ingested by a human volunteer, was absorbed almost completely from the intestine (> 87 %). The resulting adipose tissue levels, measured 13 and 69 days after dosage were 3.09±0.05 and 2.85±0.28 ppt, respectively. The dioxin was cleared from the body with a half life of elimination of 2120 days.
ISSN:0045-6535
1879-1298
DOI:10.1016/0045-6535(86)90429-7