Functional Biomaterials: Highly Elastic Micropatterned Hydrogel for Engineering Functional Cardiac Tissue (Adv. Funct. Mater. 39/2013)

Functional Biomaterials: Highly Elastic Micropatterned Hydrogel for Engineering Functional Cardiac Tissue (Adv. Funct. Mater. 39/2013)

Tropoelastin is crosslinked with methacrylation and light to make MeTro. MeTro enables encapsulation and surface interactions with cells, as shown by A. Khademhosseini, A. S. Weiss, and co‐workers on page 4950. Patterned MeTro is elastic and supports the organized growth of functionally active, beat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Advanced functional materials 2013-10, Vol.23 (39), p.4949-4949
Hauptverfasser: Annabi, Nasim, Tsang, Kelly, Mithieux, Suzanne M., Nikkhah, Mehdi, Ameri, Afshin, Khademhosseini, Ali, Weiss, Anthony S.
Format: Artikel
Sprache:eng
Schlagworte:
Biomaterials
Biomedical materials
cardiomyocyte
cell alignment
Crosslinking
elasticity
Encapsulation
Hydrogels
microfabrication
Nuclei
Surface chemistry
Surgical implants
tropoelastin
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Tropoelastin is crosslinked with methacrylation and light to make MeTro. MeTro enables encapsulation and surface interactions with cells, as shown by A. Khademhosseini, A. S. Weiss, and co‐workers on page 4950. Patterned MeTro is elastic and supports the organized growth of functionally active, beating cardiomyocytes. Immunostaining shows α‐sarcomeric actinin (green), connexin‐43 (red), and nuclei (blue).
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201370199