Production of transmitters stimulating antitumor cytostatic activity of bone marrow cells by activated lymphocytes

Production of transmitters stimulating antitumor cytostatic activity of bone marrow cells by activated lymphocytes

Murine lymphocytes preactivated with mitogen (both T and B) produce soluble transmitters which stimulate cytostatic activity of normal mouse bone marrow cells, tested byin vitro inhibition of P815 mastocytoma and L1210 lymphoma cell growth. γ-Interferon is one of T-cell products stimulating antitumo...

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Veröffentlicht in:Bulletin of experimental biology and medicine 1998-06, Vol.125 (6), p.585-587
Hauptverfasser: Seledtsov, V. I., Taraban, V. Ya, Seledtsova, G. V., Senyukov, V. V., Samarin, D. M., Kashchenko, E. A., Kozlov, V. A.
Format: Artikel
Sprache:eng
Schlagworte:
Antitumor activity
Bone marrow
Transmitters
Transplants & implants
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Zusammenfassung:Murine lymphocytes preactivated with mitogen (both T and B) produce soluble transmitters which stimulate cytostatic activity of normal mouse bone marrow cells, tested byin vitro inhibition of P815 mastocytoma and L1210 lymphoma cell growth. γ-Interferon is one of T-cell products stimulating antitumor activity of bone marrow cells. Cytostatic activity stimulated by T-cellular soluble transmitters is another characteristic of bone marrow cells isolated from nude mice.[PUBLICATION ABSTRACT]
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02445247