Genetic variations of immunoregulatory genes associated with Rasmussen syndrome

Highlights • Rasmussen syndrome (RS) had the genetic predisposition in CTLA4 , and PDCD1. • Rs231775 SNP in exon 1 of CTLA4 showed significant associations with RS. • Rs2227982 SNP in exon 5 of PDCD1 showed significant associations with RS. • SNPs of T - bet showed no association with RS.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Epilepsy research 2013-12, Vol.107 (3), p.238-243
Hauptverfasser:	Takahashi, Yukitoshi, Mogami, Yukiko, Mine, June, Imai, Katsumi, Koide, Yasumichi, Matsuda, Kazumi, Akasaka, Noriyuki, Konishi, Takashi, Imamura, Atsushi, Inoue, Yushi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Asian Continental Ancestry Group - genetics Biological and medical sciences Child Child, Preschool CTLA-4 Antigen - genetics CTLA-4 Antigen - immunology CTLA4 Encephalitis - genetics Encephalitis - immunology Epilepsy Female Genetic Predisposition to Disease Genetic Variation - immunology Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Male Medical sciences Nervous system (semeiology, syndromes) Neurology PDCD1 Polymorphism, Single Nucleotide - genetics Polymorphism, Single Nucleotide - immunology Programmed Cell Death 1 Receptor - genetics Programmed Cell Death 1 Receptor - immunology Rasmussen syndrome Retrospective Studies T-bet T-Box Domain Proteins - genetics T-Box Domain Proteins - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Rasmussen syndrome (RS) had the genetic predisposition in CTLA4 , and PDCD1. • Rs231775 SNP in exon 1 of CTLA4 showed significant associations with RS. • Rs2227982 SNP in exon 5 of PDCD1 showed significant associations with RS. • SNPs of T - bet showed no association with RS.
ISSN:	0920-1211 1872-6844
DOI:	10.1016/j.eplepsyres.2013.09.004