Comparison of instrumental methods for chlorinated dibenzo-p-dioxin (CDD) determination - interim results of a round-robin study involving GC-MS, MS-MS, and high resolution MS

A study was designed to determine the feasibility of using GC-MS-MS techniques for the determination of chlorinated dibenzo-p-dioxins (CDD) and dibenzofurans (CDF) in difficult environmental samples with reduced cleanup. Three fish and three sediment extracts were provided to six different laboratories with GC-MS-MS capability for analysis. In addition, extracts were analysed by GC-low reduction MS (LRMS) and GC-high resolution MS (HRMS). At the time of this report, all participating GC-MS-MS laboratories had not completed their analysis of the supplied samples. All reporting laboratories found the analysis of these very complex samples difficult without extensive cleanup. GC-HRMS determination of some samples was possible with reduced cleanup compared to GC-LRMS.