Carbon-14 labelled Tribendimidine, a broad-spectrum anthelmintic drug

Carbon-14 labelled Tribendimidine, a broad-spectrum anthelmintic drug

The preparation of [14C]tribendimidine, a broad‐spectrum anthelmintic agent related to amidantel, and its use during excretion and metabolism studies in the rat are described in this paper. The preparation of a 14C‐labelled version of tribendimidine, a broad‐spectrum anthelmintic agent related to am...

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Veröffentlicht in:Journal of labelled compounds & radiopharmaceuticals 2013-07, Vol.56 (9-10), p.471-474
Hauptverfasser: Fontana, Erminia, Pignatti, Alberto, Ghiglieri, Alberto, Battaglia, Rosangela, Cinato, Flavio, Wang, Chong, de Hostos, Eugenio
Format: Artikel
Sprache:eng
Schlagworte:
ADME
Animals
Anthelmintics - chemistry
Anthelmintics - metabolism
Carbon Radioisotopes - chemistry
carbon-14
Isotope Labeling
Male
Phenylenediamines - chemistry
Phenylenediamines - metabolism
rat
Rats
Rats, Sprague-Dawley
tribendimidine
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Beschreibung
Zusammenfassung:The preparation of [14C]tribendimidine, a broad‐spectrum anthelmintic agent related to amidantel, and its use during excretion and metabolism studies in the rat are described in this paper. The preparation of a 14C‐labelled version of tribendimidine, a broad‐spectrum anthelmintic agent related to amidantel, and its use during excretion and metabolism studies in the rat are described in this paper.
ISSN:0362-4803
1099-1344
DOI:10.1002/jlcr.3070