Effects of formaldehyde exposure on human NK cells in vitro
Highlights • Formaldehyde had a distinct toxicity on human NK cells. • The minimum concentration of formaldehyde to induce toxicity was 800 μM. • Formaldehyde can inhibit the adhering and cytotoxicity of NK cells. • Formaldehyde can reduce the viability and perforin secretion of NK cells.
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| Veröffentlicht in: | Environmental toxicology and pharmacology 2013-11, Vol.36 (3), p.948-955 |
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| container_issue | 3 |
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| container_title | Environmental toxicology and pharmacology |
| container_volume | 36 |
| creator | Li, Qi Mei, Qibing Huyan, Ting Xie, Li Che, Su Yang, Hui Zhang, Mingjie Huang, Qingsheng |
| description | Highlights • Formaldehyde had a distinct toxicity on human NK cells. • The minimum concentration of formaldehyde to induce toxicity was 800 μM. • Formaldehyde can inhibit the adhering and cytotoxicity of NK cells. • Formaldehyde can reduce the viability and perforin secretion of NK cells. |
| doi_str_mv | 10.1016/j.etap.2013.08.005 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1382-6689 |
| ispartof | Environmental toxicology and pharmacology, 2013-11, Vol.36 (3), p.948-955 |
| issn | 1382-6689 1872-7077 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Apoptosis - drug effects Cell Survival - drug effects Cells, Cultured Cytokines - metabolism Cytotoxicity Emergency Environmental Pollutants - toxicity Formaldehyde Formaldehyde - toxicity Granzymes - metabolism Humans In vitro Interferon-gamma - metabolism Killer Cells, Natural - drug effects Killer Cells, Natural - ultrastructure Natural killer cell Perforin - metabolism |
| title | Effects of formaldehyde exposure on human NK cells in vitro |
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