Dangers of non-specific composite outcome measures in clinical trials

Composite outcomes seem an attractive method to increase statistical power, but they can mask the effect of treatment

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Bibliographische Detailangaben
Veröffentlicht in:	BMJ (Online) 2013-11, Vol.347 (nov22 3), p.f6782-f6782
Hauptverfasser:	Prieto-Merino, David, Smeeth, Liam, Staa, Tjeerd P van, Roberts, Ian
Format:	Artikel
Sprache:	eng
Schlagworte:	Causality Chronic obstructive pulmonary disease Clinical trials Clinical Trials as Topic - methods Humans Mortality Outcome Assessment (Health Care) - methods Pharmaceuticals Research Design Research Methods & Reporting Statistics as Topic Treatment Outcome
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Composite outcomes seem an attractive method to increase statistical power, but they can mask the effect of treatment
ISSN:	0959-8138 1756-1833 1756-1833
DOI:	10.1136/bmj.f6782