Polymorphic Ventricular Tachycardia–Part II: The Channelopathies

Abstract In this article, we explore the clinical and cellular phenomena of primary electrical diseases of the heart, that is, conditions purely related to ion channel dysfunction and not structural heart disease or reversible acquired causes. This growing classification of conditions, once consider...

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Veröffentlicht in:	Current problems in cardiology 2013-12, Vol.38 (12), p.503-548
Hauptverfasser:	Choudhuri, Indrajit, MD, Pinninti, Mamatha, MD, Marwali, Muhammad R., MD, Sra, Jasbir, MD, Akhtar, Masood, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrhythmias, Cardiac - diagnosis Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - therapy Brugada Syndrome - diagnosis Brugada Syndrome - etiology Brugada Syndrome - therapy Cardiovascular Channelopathies - complications Electrocardiography Genetic Predisposition to Disease Genetic Testing Humans Long QT Syndrome - diagnosis Long QT Syndrome - etiology Long QT Syndrome - therapy Prognosis Tachycardia, Ventricular - diagnosis Tachycardia, Ventricular - etiology Tachycardia, Ventricular - therapy Torsades de Pointes - diagnosis Torsades de Pointes - etiology Torsades de Pointes - therapy
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Zusammenfassung:	Abstract In this article, we explore the clinical and cellular phenomena of primary electrical diseases of the heart, that is, conditions purely related to ion channel dysfunction and not structural heart disease or reversible acquired causes. This growing classification of conditions, once considered together as “idiopathic ventricular fibrillation,” continues to evolve and segregate into diseases that are phenotypically, molecularly, and genetically unique.
ISSN:	0146-2806 1535-6280
DOI:	10.1016/j.cpcardiol.2013.07.004