Personalized Network-Based Treatments in Oncology

Network medicine aims at unraveling cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technologi...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2013-12, Vol.94 (6), p.646-650
Hauptverfasser:	Robin, X, Creixell, P, Radetskaya, O, Santini, CC, Longden, J, Linding, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Combined Chemotherapy Protocols - pharmacology Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomarkers - metabolism Drug Design Humans Medical sciences Molecular Targeted Therapy Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - drug therapy Neoplasms - metabolism Pharmacology. Drug treatments Precision Medicine - methods Protein Interaction Maps Protein Processing, Post-Translational Signal Transduction Systems Biology Tumors
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Beschreibung
Zusammenfassung:	Network medicine aims at unraveling cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technological and scientific developments in both drug design and signaling network analysis. Clinical Pharmacology & Therapeutics (2013); 94 6, 646–650. doi:10.1038/clpt.2013.171
ISSN:	0009-9236 1532-6535
DOI:	10.1038/clpt.2013.171