Immunoenzymatic determination of antibody-bound soluble antigens ofTrypanosoma cruzi

Anti-Major Cathodic Antigen (MCA) monospecific immunoglobulins ofT. cruzi have been used for the preparation of polyamide-linked immunoadsorbents. A high proportion of serologically positive patients with Chagas disease show the presence of a soluble antigen complexed with human immunoglobulins, whi...

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Veröffentlicht in:Applied biochemistry and biotechnology 1982-11, Vol.7 (6), p.459-462
Hauptverfasser: Marcipar, A, Barnes, S, Lentwojt, E, Broun, G
Format: Artikel
Sprache:eng
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Zusammenfassung:Anti-Major Cathodic Antigen (MCA) monospecific immunoglobulins ofT. cruzi have been used for the preparation of polyamide-linked immunoadsorbents. A high proportion of serologically positive patients with Chagas disease show the presence of a soluble antigen complexed with human immunoglobulins, which complex binds to those immunoadsorbents as determined by a double sandwich reaction and a peroxidase final determination.
ISSN:0273-2289
1559-0291
DOI:10.1007/BF02799177