A highly specific BODIPY-based probe localized in mitochondria for HClO imaging
An oxime containing fluorescent probe based on a BODIPY scaffold was successfully designed and used for HClO determination with rapid response, low detection limits and high selectivity. Confocal fluorescence microscopy demonstrated that the probe could permeate the mitochondria and made possible th...
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| Veröffentlicht in: | Analyst (London) 2013-10, Vol.138 (20), p.6091-6096 |
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| container_issue | 20 |
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| container_title | Analyst (London) |
| container_volume | 138 |
| creator | Cheng, Guanghui Fan, Jiangli Sun, Wen Sui, Kun Jin, Xin Wang, Jingyun Peng, Xiaojun |
| description | An oxime containing fluorescent probe based on a BODIPY scaffold was successfully designed and used for HClO determination with rapid response, low detection limits and high selectivity. Confocal fluorescence microscopy demonstrated that the probe could permeate the mitochondria and made possible the fast fluorescent imaging of endogenous HClO. |
| doi_str_mv | 10.1039/c3an01152f |
| format | Article |
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| ispartof | Analyst (London), 2013-10, Vol.138 (20), p.6091-6096 |
| issn | 0003-2654 1364-5528 |
| language | eng |
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| source | MEDLINE; Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Boron Compounds - chemistry Confocal Fluorescence Fluorescent Dyes - chemistry Humans Hypochlorous Acid - chemistry Imaging MCF-7 Cells Microscopy Mitochondria Mitochondria - chemistry Oximes Scaffolds Spectrometry, Fluorescence - methods |
| title | A highly specific BODIPY-based probe localized in mitochondria for HClO imaging |
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