Brain Structure in Adolescents and Young Adults with Alcohol Problems: Systematic Review of Imaging Studies

Alcohol-dependent people who are middle-aged or older have a widespread loss of cortical grey and white matter, particularly in the prefrontal cortex (PFC). We examine if brain abnormalities are detectable in alcohol use disorders before the fifth decade (i.e.,

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Bibliographische Detailangaben
Veröffentlicht in:	Alcohol and alcoholism (Oxford) 2013-07, Vol.48 (4), p.433-444
Hauptverfasser:	WELCH, Killian A, CARSON, Alan, LAWRIE, Stephen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adolescents Adult and adolescent clinical studies Age Factors Alcohol abuse Alcohol dependence Alcohol-Related Disorders - pathology Alcoholism Alcoholism and acute alcohol poisoning Atrophy - pathology Biological and medical sciences Brain structure Case-Control Studies Corpus Callosum - pathology Cortex Hippocampus - pathology Humans Medical sciences Neuroimaging Prefrontal Cortex - pathology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Sex Characteristics Toxicology Young adults
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Beschreibung
Zusammenfassung:	Alcohol-dependent people who are middle-aged or older have a widespread loss of cortical grey and white matter, particularly in the prefrontal cortex (PFC). We examine if brain abnormalities are detectable in alcohol use disorders before the fifth decade (i.e.,
ISSN:	0735-0414 1464-3502
DOI:	10.1093/alcalc/agt037