Safety and efficacy of total dose infusion of 1,020 mg of ferumoxytol administered over 15 min

For the majority of patients with iron deficiency anemia (IDA), a full course of intravenous (IV) iron is 1 g. Most IV irons require 5–10 administrations of 100–300 mg. We have successfully employed 1 g low molecular weight iron dextran over 1 hr. For further convenience for patients and physicians,...

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Veröffentlicht in:American journal of hematology 2013-11, Vol.88 (11), p.944-947
Hauptverfasser: Auerbach, Michael, Strauss, William, Auerbach, Sarah, Rineer, Stella, Bahrain, Huzefa
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Sprache:eng
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Zusammenfassung:For the majority of patients with iron deficiency anemia (IDA), a full course of intravenous (IV) iron is 1 g. Most IV irons require 5–10 administrations of 100–300 mg. We have successfully employed 1 g low molecular weight iron dextran over 1 hr. For further convenience for patients and physicians, we explored the administration of 1.02 g of ferumoxytol over 15 min instead of the approved 2 × 510 mg injections. Sixty patients with IDA, (hemoglobin
ISSN:0361-8609
1096-8652
DOI:10.1002/ajh.23534