Pyrrolizidine Alkaloids from Onosma erecta

Pyrrolizidine Alkaloids from Onosma erecta

The MeOH extract of the aerial parts of Onosma erecta afforded four new pyrrolizidine alkaloids, 7-O-acetylechinatine N-oxide (1), a viridinatine N-oxide stereoisomer (2), 7-epi-echimiplatine N-oxide (3), and onosmerectine N-oxide (4), and two additional new natural products, the acid 2,3-dimethyl-2...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 2013-10, Vol.76 (10), p.1829-1835
Hauptverfasser: Damianakos, Harilaos, Sotiroudis, Georgios, Chinou, Ioanna
Format: Artikel
Sprache:eng
Schlagworte:
Boraginaceae - chemistry
Chromatography, High Pressure Liquid
Greece
Humans
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Pyrrolizidine Alkaloids - chemistry
Pyrrolizidine Alkaloids - isolation & purification
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Zusammenfassung:The MeOH extract of the aerial parts of Onosma erecta afforded four new pyrrolizidine alkaloids, 7-O-acetylechinatine N-oxide (1), a viridinatine N-oxide stereoisomer (2), 7-epi-echimiplatine N-oxide (3), and onosmerectine N-oxide (4), and two additional new natural products, the acid 2,3-dimethyl-2,3,4-trihydroxypentanoic acid (5) and the acyloin 4-methyl-2-hydroxypentanone (6).
ISSN:0163-3864
1520-6025
DOI:10.1021/np300785g