Immunochemistry screening for Lynch syndrome in colorectal adenocarcinoma using an initial two antibody panel can replace a four antibody panel

Tests the hypothesis that staining for PMS2 and MSH6 antibodies alone will be sufficient to detect all cases of Lynch syndrome (LS) - also known as hereditary non polyposis colorectal cancer (HNPCC), an inherited autosomal dominant condition predisposing to early onset colorectal adenocarcinoma - an...

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