Phenolic profiling of the skin, pulp and seeds of Albariño grapes using hybrid quadrupole time-of-flight and triple-quadrupole mass spectrometry

•For the first time a characterisation of the phenolic compounds in skin, pulp and seed of the Albariño grape was reported.•The combination of QqToF and QqQ enabled us to identify 43 polyphenols in skin, pulp and seed of Albariño grape.•The compounds were confirmed by accurate mass measurements in QqToF-MS and QqToF-MS/MS modes at high resolution.•Two phenolic compounds, such as (epi)catechin-hexosides, as far as we know, were reported for the first time in grapes. This paper describes for the first time a complete characterisation of the phenolic compounds in different anatomical parts of the Albariño grape. The application of high-performance liquid chromatography coupled with two complementary techniques, hybrid quadrupole time-of-flight and triple-quadrupole mass spectrometry, allowed the phenolic composition of the Albariño grape to be unambiguously identified and quantified. A more complete phenolic profile was obtained by product ion and precursor ion scans, while a neutral loss scan at 152 u enabled a fast screening of procyanidin dimers, trimers and their galloylated derivatives. The compounds were confirmed by accurate mass measurements in QqToF-MS and QqToF-MS/MS modes at high resolution, and good fits were obtained for all investigated ions, with errors ranging from 0.2 to 4.5 mDa. To the best of our knowledge, two flavanol monomer hexosides were detected in the grape berry for the first time.