Identification of a novel alternative splicing variant of hemocyanin from shrimp Litopenaeus vannamei

Highlights • We found for the first time a novel alternative splicing variant of hemocyanin (cHE1) in shrimp. • The isoform might be generated by retention of introns. • cHE1 transcripts showed a significant up-regulation in pathogen-treated shrimps.

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Bibliographische Detailangaben
Veröffentlicht in:	Immunology letters 2013-07, Vol.154 (1), p.1-6
Hauptverfasser:	Zhao, Shan, Lu, Xin, Zhang, Yueling, Zhao, Xianliang, Zhong, Mingqi, Li, Shengkang, Lun, Jingsheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Alternative Splicing Alternative splicing variant Amino Acid Sequence Animals Artemia Cells, Cultured cHE1 Hemocyanin Hemocyanins - genetics Hemocyanins - metabolism Immunity Larva Litopenaeus vannamei Molecular Sequence Data Myocardium - metabolism Poly I-C - immunology Protein Isoforms - genetics Protein Isoforms - metabolism Up-Regulation Vibrio Infections - immunology Vibrio parahaemolyticus - immunology
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Beschreibung
Zusammenfassung:	Highlights • We found for the first time a novel alternative splicing variant of hemocyanin (cHE1) in shrimp. • The isoform might be generated by retention of introns. • cHE1 transcripts showed a significant up-regulation in pathogen-treated shrimps.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2013.08.003