Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis

The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2013-11, Vol.49 (88), p.10349-10351
Hauptverfasser: Kim, Seol-Hee, Kim, Jong-Ho, You, Dong Gil, Saravanakumar, Gurusamy, Yoon, Hong Yeol, Choi, Ki Young, Thambi, Thavasyappan, Deepagan, V G, Jo, Dong-Gyu, Park, Jae Hyung
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container_end_page 10351
container_issue 88
container_start_page 10349
container_title Chemical communications (Cambridge, England)
container_volume 49
creator Kim, Seol-Hee
Kim, Jong-Ho
You, Dong Gil
Saravanakumar, Gurusamy
Yoon, Hong Yeol
Choi, Ki Young
Thambi, Thavasyappan
Deepagan, V G
Jo, Dong-Gyu
Park, Jae Hyung
description The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.
doi_str_mv 10.1039/c3cc44260h
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source MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection
subjects Animals
Arthritis, Rheumatoid - drug therapy
Click Chemistry
Dextran Sulfate - chemistry
Drug Carriers - chemistry
Hydrophobic and Hydrophilic Interactions
Mice
Molecular Targeted Therapy
Nanoparticles - chemistry
Polyesters - chemistry
title Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis
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