Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis
The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.
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Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2013-11, Vol.49 (88), p.10349-10351 |
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container_title | Chemical communications (Cambridge, England) |
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creator | Kim, Seol-Hee Kim, Jong-Ho You, Dong Gil Saravanakumar, Gurusamy Yoon, Hong Yeol Choi, Ki Young Thambi, Thavasyappan Deepagan, V G Jo, Dong-Gyu Park, Jae Hyung |
description | The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis. |
doi_str_mv | 10.1039/c3cc44260h |
format | Article |
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Kim, Jong-Ho ; You, Dong Gil ; Saravanakumar, Gurusamy ; Yoon, Hong Yeol ; Choi, Ki Young ; Thambi, Thavasyappan ; Deepagan, V G ; Jo, Dong-Gyu ; Park, Jae Hyung</creator><creatorcontrib>Kim, Seol-Hee ; Kim, Jong-Ho ; You, Dong Gil ; Saravanakumar, Gurusamy ; Yoon, Hong Yeol ; Choi, Ki Young ; Thambi, Thavasyappan ; Deepagan, V G ; Jo, Dong-Gyu ; Park, Jae Hyung</creatorcontrib><description>The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c3cc44260h</identifier><identifier>PMID: 23942894</identifier><language>eng</language><publisher>England</publisher><subject>Animals ; Arthritis, Rheumatoid - drug therapy ; Click Chemistry ; Dextran Sulfate - chemistry ; 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source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
subjects | Animals Arthritis, Rheumatoid - drug therapy Click Chemistry Dextran Sulfate - chemistry Drug Carriers - chemistry Hydrophobic and Hydrophilic Interactions Mice Molecular Targeted Therapy Nanoparticles - chemistry Polyesters - chemistry |
title | Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis |
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