Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis

The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2013-11, Vol.49 (88), p.10349-10351
Hauptverfasser:	Kim, Seol-Hee, Kim, Jong-Ho, You, Dong Gil, Saravanakumar, Gurusamy, Yoon, Hong Yeol, Choi, Ki Young, Thambi, Thavasyappan, Deepagan, V G, Jo, Dong-Gyu, Park, Jae Hyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Rheumatoid - drug therapy Click Chemistry Dextran Sulfate - chemistry Drug Carriers - chemistry Hydrophobic and Hydrophilic Interactions Mice Molecular Targeted Therapy Nanoparticles - chemistry Polyesters - chemistry
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Beschreibung
Zusammenfassung:	The amphiphilic block copolymer, composed of hydrophilic dextran sulfate as the targeting ligand and hydrophobic polycaprolactone as the hydrophobic segment, was prepared via click chemistry to develop self-assembled nanoparticles for targeting rheumatoid arthritis.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c3cc44260h