Waist circumference is associated with carotid intima media thickness in peritoneal dialysis patients

Purpose Atherosclerosis is responsible for the high mortality rate in end-stage renal disease patients. Defining risk factors for atherosclerosis may lead to reduction in cardiovascular disease through modification of these factors. Peritoneal dialysis (PD) patients are subjected to high glucose loa...

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Veröffentlicht in:International urology and nephrology 2013-10, Vol.45 (5), p.1437-1443
Hauptverfasser: Asicioglu, Ebru, Kahveci, Arzu, Arikan, Hakkı, Koc, Mehmet, Tuglular, Serhan, Ozener, Cetin Ishak
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Sprache:eng
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Zusammenfassung:Purpose Atherosclerosis is responsible for the high mortality rate in end-stage renal disease patients. Defining risk factors for atherosclerosis may lead to reduction in cardiovascular disease through modification of these factors. Peritoneal dialysis (PD) patients are subjected to high glucose loads on a daily basis, which results in considerable weight gain and an increase in waist circumference (WC). WC as an indicator of abdominal obesity is a risk factor for atherosclerosis in the general population. Carotid artery intima media thickness (CIMT) measurement is a reliable method for the detection of early atherosclerosis. The aim of this study was to investigate the relationship between WC and CIMT and to define risk factors associated with CIMT in PD patients. Methods Fifty-five PD patients and 40 healthy controls were included. Atherosclerosis was assessed using measurement of CIMT. Fasting blood was collected for analysis. Anthropometric parameters (age, weight, BMI, and WC) were measured. Results Peritoneal dialysis patients had higher WC (93.9 ± 1.7 vs. 87.3 ± 1.2 cm, p  
ISSN:0301-1623
1573-2584
DOI:10.1007/s11255-013-0427-x